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isoionic point
The isoionic point is the pH value at which a zwitterion molecule has an equal number of positive and negative charges and no adherent ionic species. It was first defined by S.P.L. Sørensen, Kaj Ulrik Linderstrøm-Lang and Ellen Lund in 1926 〔Sørensen S.P.L., Linderstrøm-Lang K., and Lund E (1926). 'The influence of salt concentration on the acid-binding capacity of egg-albuminin'. J. Gen. Physiol., Mar 1927; 8: 543 - 599〕 and is mainly a term used in protein sciences.
It is different from the isoelectric point (p''I'') in that p''I'' is the pH value at which the net charge of the molecule, ''including'' bound ions is zero. Whereas the isoionic point is at net charge zero in a deionized solution. Thus, the isoelectric and isoionic points are equal when the concentration of charged species is zero.
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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